Parameter estimation in biochemical pathways: a comparison of global optimization methods

Here we address the problem of parameter estimation (inverse problem) of nonlinear dynamic biochemical pathways. This problem is stated as a nonlinear programming (NLP) problem subject to nonlinear differential-algebraic constraints. These problems are known to be frequently ill-conditioned and mult...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Genome research Ročník 13; číslo 11; s. 2467
Hlavní autori:	Moles, Carmen G, Mendes, Pedro, Banga, Julio R
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.11.2003
Predmet:	Algorithms Computational Biology - methods Computational Biology - statistics & numerical data Computer Simulation Evolution, Molecular Genetic Engineering - methods HIV Protease - chemistry HIV Protease - genetics HIV Protease - metabolism HIV Protease Inhibitors - chemistry Models, Chemical Molecular Biology - methods Molecular Biology - statistics & numerical data Nonlinear Dynamics Predictive Value of Tests Software - statistics & numerical data Stochastic Processes
ISSN:	1088-9051
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!