Spindle-E Acts Antivirally Against Alphaviruses in Mosquito Cells

Mosquitoes transmit several human- and animal-pathogenic alphaviruses (Togaviridae family). In alphavirus-infected mosquito cells two different types of virus-specific small RNAs are produced as part of the RNA interference response: short-interfering (si)RNAs and PIWI-interacting (pi)RNAs. The siRN...

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Veröffentlicht in:	Viruses Jg. 10; H. 2; S. 88
Hauptverfasser:	Varjak, Margus, Dietrich, Isabelle, Sreenu, Vattipally B., Till, Bethan Eluned, Merits, Andres, Kohl, Alain, Schnettler, Esther
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 18.02.2018 MDPI
Schlagworte:	Ae. aegypti Aedes aegypti Alphavirus Alphavirus Infections - virology Animals Antiviral activity Antiviral drugs antiviral responses Argonaute 2 protein Cells, Cultured Culicidae - virology DNA helicase Insect Proteins - genetics Mosquitoes Replication RNA Interference RNA, Small Untranslated - genetics RNA-mediated interference siRNA Virus Replication antiviral responses RNA interference alphavirus Ae. aegypti
ISSN:	1999-4915, 1999-4915
Online-Zugang:	Volltext
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