Reduced repair of the oxidative 8-oxoguanine DNA damage and risk of head and neck cancer

An increasing number of studies indicate that reduced DNA-repair capacity is associated with increased cancer risk. Using a functional assay for the removal of the oxidative DNA lesion 8-oxoguanine by the DNA-repair enzyme 8-oxoguanine DNA glycosylase 1 (OGG1), we have previously shown that reduced...

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Bibliographic Details
Published in:	Cancer research (Chicago, Ill.) Vol. 66; no. 24; p. 11683
Main Authors:	Paz-Elizur, Tamar, Ben-Yosef, Rami, Elinger, Dalia, Vexler, Akiva, Krupsky, Meir, Berrebi, Alain, Shani, Adi, Schechtman, Edna, Freedman, Laurence, Livneh, Zvi
Format:	Journal Article
Language:	English
Published:	United States 15.12.2006
Subjects:	Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - epidemiology Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology DNA Damage DNA Repair - genetics Female Guanine - analogs & derivatives Head and Neck Neoplasms - epidemiology Head and Neck Neoplasms - genetics Head and Neck Neoplasms - pathology Humans Male Middle Aged Neoplasm Staging Oxidation-Reduction Reference Values Risk Factors Surveys and Questionnaires
ISSN:	0008-5472
Online Access:	Get more information
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