Molecular signatures in Mendelian neurodevelopment: a focus on ubiquitination driven DNA methylation aberrations

Mendelian disorders, arising from pathogenic variations within single genetic loci, often manifest as neurodevelopmental disorders (NDDs), affecting a significant portion of the pediatric population worldwide. These disorders are marked by atypical brain development, intellectual disabilities, and v...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Frontiers in molecular neuroscience Jg. 17; S. 1446686
Hauptverfasser:	van der Laan, Liselot, ten Voorde, Nicky, Mannens, Marcel M. A. M., Henneman, Peter
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 29.07.2024
Schlagworte:	DNA methylation epigenetic machinery Mendelian disorders Molecular Neuroscience TRIP12 ubiquitination pathway USP7 DNA methylation USP7 TRIP12 epigenetic machinery ubiquitination pathway Mendelian disorders
ISSN:	1662-5099, 1662-5099
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!