Mendelian randomization indicates causal effects of estradiol levels on kidney function in males

Chronic kidney disease (CKD) is a public health burden worldwide. Epidemiological studies observed an association between sex hormones, including estradiol, and kidney function. We conducted a Mendelian randomization (MR) study to assess a possible causal effect of estradiol levels on kidney functio...

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Bibliographic Details
Published in:	Frontiers in endocrinology (Lausanne) Vol. 14; p. 1232266
Main Authors:	Nasr, M. Kamal, Schurmann, Claudia, Böttinger, Erwin P., Teumer, Alexander
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 19.12.2023
Subjects:	albuminuria causality Cohort Studies Endocrinology Estradiol Female Genome-Wide Association Study glomerular filtration rate Humans Kidney Male Mendelian Randomization Analysis Renal Insufficiency, Chronic - etiology Renal Insufficiency, Chronic - genetics steroids albuminuria steroids glomerular filtration rate genome-wide association study causality
ISSN:	1664-2392, 1664-2392
Online Access:	Get full text
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