Determinants of asthma phenotypes in supermarket bakery workers
While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma phenotypes in supermarket bakery workers in relation to host risk factors and self-reported exposure to flour dust. A cross-sectional stu...
Saved in:
| Published in: | The European respiratory journal Vol. 34; no. 4; p. 825 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
01.10.2009
|
| Subjects: | |
| ISSN: | 1399-3003, 1399-3003 |
| Online Access: | Get more information |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma phenotypes in supermarket bakery workers in relation to host risk factors and self-reported exposure to flour dust. A cross-sectional study of 517 supermarket bakery workers in 31 bakeries used a questionnaire, skin prick tests, and specific immunoglobulin E to wheat, rye and fungal alpha-amylase and methacholine challenge testing. The prevalence of probable occupational asthma (OA, 13%) was higher than atopic (6%), nonatopic (6%) and work-aggravated asthma (WAA, 3%) phenotypes. Previous episodes of high exposure to dusts, fumes and vapours causing asthma symptoms were more strongly associated with WAA (OR 5.8, 95% CI 1.7-19.2) than OA (2.8, 1.4-5.5). Work-related ocular-nasal symptoms were significantly associated with WAA (4.3, 1.3-13.8) and OA (3.1, 1.8-5.5). Bakers with OA had an increased odds ratio of reporting adverse reactions to ingested grain products (6.4, 2.0-19.8). OA is the most common phenotype among supermarket bakery workers. Analysis of risk factors contributes to defining clinical phenotypes, which will guide ongoing medical surveillance and clinical management of bakery workers. |
|---|---|
| AbstractList | While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma phenotypes in supermarket bakery workers in relation to host risk factors and self-reported exposure to flour dust. A cross-sectional study of 517 supermarket bakery workers in 31 bakeries used a questionnaire, skin prick tests, and specific immunoglobulin E to wheat, rye and fungal alpha-amylase and methacholine challenge testing. The prevalence of probable occupational asthma (OA, 13%) was higher than atopic (6%), nonatopic (6%) and work-aggravated asthma (WAA, 3%) phenotypes. Previous episodes of high exposure to dusts, fumes and vapours causing asthma symptoms were more strongly associated with WAA (OR 5.8, 95% CI 1.7-19.2) than OA (2.8, 1.4-5.5). Work-related ocular-nasal symptoms were significantly associated with WAA (4.3, 1.3-13.8) and OA (3.1, 1.8-5.5). Bakers with OA had an increased odds ratio of reporting adverse reactions to ingested grain products (6.4, 2.0-19.8). OA is the most common phenotype among supermarket bakery workers. Analysis of risk factors contributes to defining clinical phenotypes, which will guide ongoing medical surveillance and clinical management of bakery workers.While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma phenotypes in supermarket bakery workers in relation to host risk factors and self-reported exposure to flour dust. A cross-sectional study of 517 supermarket bakery workers in 31 bakeries used a questionnaire, skin prick tests, and specific immunoglobulin E to wheat, rye and fungal alpha-amylase and methacholine challenge testing. The prevalence of probable occupational asthma (OA, 13%) was higher than atopic (6%), nonatopic (6%) and work-aggravated asthma (WAA, 3%) phenotypes. Previous episodes of high exposure to dusts, fumes and vapours causing asthma symptoms were more strongly associated with WAA (OR 5.8, 95% CI 1.7-19.2) than OA (2.8, 1.4-5.5). Work-related ocular-nasal symptoms were significantly associated with WAA (4.3, 1.3-13.8) and OA (3.1, 1.8-5.5). Bakers with OA had an increased odds ratio of reporting adverse reactions to ingested grain products (6.4, 2.0-19.8). OA is the most common phenotype among supermarket bakery workers. Analysis of risk factors contributes to defining clinical phenotypes, which will guide ongoing medical surveillance and clinical management of bakery workers. While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma phenotypes in supermarket bakery workers in relation to host risk factors and self-reported exposure to flour dust. A cross-sectional study of 517 supermarket bakery workers in 31 bakeries used a questionnaire, skin prick tests, and specific immunoglobulin E to wheat, rye and fungal alpha-amylase and methacholine challenge testing. The prevalence of probable occupational asthma (OA, 13%) was higher than atopic (6%), nonatopic (6%) and work-aggravated asthma (WAA, 3%) phenotypes. Previous episodes of high exposure to dusts, fumes and vapours causing asthma symptoms were more strongly associated with WAA (OR 5.8, 95% CI 1.7-19.2) than OA (2.8, 1.4-5.5). Work-related ocular-nasal symptoms were significantly associated with WAA (4.3, 1.3-13.8) and OA (3.1, 1.8-5.5). Bakers with OA had an increased odds ratio of reporting adverse reactions to ingested grain products (6.4, 2.0-19.8). OA is the most common phenotype among supermarket bakery workers. Analysis of risk factors contributes to defining clinical phenotypes, which will guide ongoing medical surveillance and clinical management of bakery workers. |
| Author | Sander, I Bateman, E D Robins, T G Raulf-Heimsoth, M Baatjies, R Jeebhay, M F Lopata, A L Meijster, T Heederik, D |
| Author_xml | – sequence: 1 givenname: R surname: Baatjies fullname: Baatjies, R organization: Centre for Occupational and Environmental Health Research Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa – sequence: 2 givenname: A L surname: Lopata fullname: Lopata, A L – sequence: 3 givenname: I surname: Sander fullname: Sander, I – sequence: 4 givenname: M surname: Raulf-Heimsoth fullname: Raulf-Heimsoth, M – sequence: 5 givenname: E D surname: Bateman fullname: Bateman, E D – sequence: 6 givenname: T surname: Meijster fullname: Meijster, T – sequence: 7 givenname: D surname: Heederik fullname: Heederik, D – sequence: 8 givenname: T G surname: Robins fullname: Robins, T G – sequence: 9 givenname: M F surname: Jeebhay fullname: Jeebhay, M F |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/19443530$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNj01LAzEYhINUrK3-AC-Sm6etb_JmP3ISqZ9Q8KLnJZu8S9d2s-smi_TfW7WCp5mBh2Fmxia-88TYhYCFEAVegwYUGrMFgMiUguKInQrUOkEAnPzzUzYL4f2HQnHCpkIrhSnCKbu5o0hD23jjY-BdzU2I69bwfk2-i7ueAm88D2O_h8ywocgrs6Fhxz-7fRrCGTuuzTbQ-UHn7O3h_nX5lKxeHp-Xt6vEqkzHJK9klQtLztmisjUJBw6dNpQahAxV7XKTaylJOsjTikRBVspaWyfAFljIObv67e2H7mOkEMu2CZa2W-OpG0OZo4JMq_SbvDyQY9WSK_uh2S_flX-f5RftSlvT |
| CitedBy_id | crossref_primary_10_4168_aair_2013_5_6_348 crossref_primary_10_1016_j_reval_2011_01_048 crossref_primary_10_1002_ajim_22041 crossref_primary_10_7189_jogh_11_04026 crossref_primary_10_1016_j_jaci_2014_03_016 crossref_primary_10_1002_ajim_22841 crossref_primary_10_1513_AnnalsATS_201305_119ST crossref_primary_10_1093_annhyg_meq005 crossref_primary_10_3390_microorganisms8010118 crossref_primary_10_1186_s13223_015_0080_2 crossref_primary_10_3389_fnut_2020_00006 crossref_primary_10_1136_oemed_2013_101853 crossref_primary_10_1155_2020_3767382 crossref_primary_10_1097_ACI_0000000000000042 crossref_primary_10_1136_oemed_2013_101971 crossref_primary_10_2500_aap_2021_42_200090 crossref_primary_10_1002_ajim_20893 crossref_primary_10_1155_2011_682574 crossref_primary_10_4236_health_2024_163017 crossref_primary_10_1371_journal_pone_0216568 crossref_primary_10_1007_s00420_019_01511_7 crossref_primary_10_1007_s00420_021_01698_8 crossref_primary_10_1016_j_reval_2016_01_052 crossref_primary_10_1093_mmy_myab023 crossref_primary_10_1111_all_13807 crossref_primary_10_3233_WOR_220165 crossref_primary_10_1097_JOM_0000000000000706 crossref_primary_10_1093_bmb_ldu004 crossref_primary_10_1093_occmed_kqac101 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1183/09031936.00164408 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1399-3003 |
| ExternalDocumentID | 19443530 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GeographicLocations | South Africa |
| GeographicLocations_xml | – name: South Africa |
| GroupedDBID | --- .55 .GJ 18M 1OC 2WC 31~ 3O- 53G 5GY 5RE 5VS 8-1 AADJU AAFWJ AAZMJ ABCQX ABJNI ABOCM ABSQV ACEMG ACGFO ACPRK ACXQS ADBBV ADDZX ADMOG ADYFA AENEX AFFNX AFHIN AFZJQ AIZTS AJAOE ALMA_UNASSIGNED_HOLDINGS BAWUL BTFSW CAG CGR COF CS3 CUY CVF DIK E3Z EBS ECM EIF EJD F5P F9R GX1 H13 INIJC J5H KQ8 L7B LH4 LW6 NPM OK1 P2P PQQKQ R0Z RHI TER TR2 W8F WOQ X7M ZE2 ZGI ZXP ~02 7X8 |
| ID | FETCH-LOGICAL-c469t-7b2b71ceddc8bcfe1d0d3d9ae5a30634fd7a7922e2d075be18ec22f9cd10c8382 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 44 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000270662200008&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1399-3003 |
| IngestDate | Fri Sep 05 06:20:18 EDT 2025 Thu Apr 03 06:59:20 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c469t-7b2b71ceddc8bcfe1d0d3d9ae5a30634fd7a7922e2d075be18ec22f9cd10c8382 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://erj.ersjournals.com/content/erj/34/4/825.full.pdf |
| PMID | 19443530 |
| PQID | 734069458 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_734069458 pubmed_primary_19443530 |
| PublicationCentury | 2000 |
| PublicationDate | 2009-10-01 |
| PublicationDateYYYYMMDD | 2009-10-01 |
| PublicationDate_xml | – month: 10 year: 2009 text: 2009-10-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | The European respiratory journal |
| PublicationTitleAlternate | Eur Respir J |
| PublicationYear | 2009 |
| SSID | ssj0016431 |
| Score | 2.1826622 |
| Snippet | While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 825 |
| SubjectTerms | Adult Asthma - diagnosis Asthma - epidemiology Asthma - physiopathology Cross-Sectional Studies Dust Female Flour - adverse effects Food Industry Humans Male Occupational Diseases - diagnosis Occupational Diseases - epidemiology Occupational Diseases - physiopathology Occupational Exposure - statistics & numerical data Phenotype Prevalence Prospective Studies Respiratory Hypersensitivity - diagnosis Respiratory Hypersensitivity - epidemiology Respiratory Hypersensitivity - physiopathology Risk Factors Secale - adverse effects Skin Tests South Africa - epidemiology Surveys and Questionnaires Triticum - adverse effects Young Adult |
| Title | Determinants of asthma phenotypes in supermarket bakery workers |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/19443530 https://www.proquest.com/docview/734069458 |
| Volume | 34 |
| WOSCitedRecordID | wos000270662200008&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV07T8MwED4BRYiF96O85IE1amInjTNVCKgYaNUBULfIsR1RIZLStEj8e-6cFFgQA0s2R9HlfPedv-98AJeCJ8o3oXYdPVig5NKTXYPbXUeUfo20ro_76T4eDuV4nIwabU7VyCqXMdEFalNqOiPvxML1aEayN33zaGgUkavNBI1VaAlEMuTU8fibRMBkW9dbCdH7vmhITXTiDp1OIHRxRESXhi7_DjBdoulv__MTd2CrQZjsqnaJXVixxR5sDBoOfR96Nz8UMKzMmarmz6-KkdirpBPZik0KVi2mFLOpJZpl6sXOPhhJuBAsHsBj__bh-s5rxih4GmvfuRdnPIsDbY3RMtO5DYxvhEmUjRTWCyLMTazihHPLDeKHzAbSas7zRJvA11JIfghrRVnYY2C4wEhCGEKpMMLXhcbnKiBQKDOMBW1gS8uk6KbEPajClosq_bJNG45q66bT-jqNNEhCxGzCP_l78SlsOjbHienOoJXjFrXnsK7f55NqduF-Pz6Ho8EnwtO5EQ |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Determinants+of+asthma+phenotypes+in+supermarket+bakery+workers&rft.jtitle=The+European+respiratory+journal&rft.au=Baatjies%2C+R&rft.au=Lopata%2C+A+L&rft.au=Sander%2C+I&rft.au=Raulf-Heimsoth%2C+M&rft.date=2009-10-01&rft.issn=1399-3003&rft.eissn=1399-3003&rft.volume=34&rft.issue=4&rft.spage=825&rft_id=info:doi/10.1183%2F09031936.00164408&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1399-3003&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1399-3003&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1399-3003&client=summon |