In the absence of streptomycin, minoxidil potentiates the mitogenic effects of fetal calf serum, insulin-like growth factor 1, and platelet-derived growth factor on NIH 3T3 fibroblasts in a K+ channel-dependent fashion

There is considerable evidence to suggest that the opening of K+ channels plays an important role in stimulating mitogenesis. K+ channel blockers have been shown to inhibit mitogenesis in vitro, mitogens increase cytosolic membrane K+ channel permeability, K+ channel openers stimulate hair growth in...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of investigative dermatology Vol. 107; no. 2; p. 229
Main Authors:	Sanders, D A, Fiddes, I, Thompson, D M, Philpott, M P, Westgate, G E, Kealey, T
Format:	Journal Article
Language:	English
Published:	United States 01.08.1996
Subjects:	3T3 Cells - drug effects 3T3 Cells - physiology Animals Cattle - blood Cattle - embryology Cell Division - drug effects Fetal Blood - physiology Fibroblasts - drug effects Fibroblasts - physiology Growth Substances - pharmacology Insulin-Like Growth Factor I - pharmacology Mice Minoxidil - pharmacology Mitogens - pharmacology Platelet-Derived Growth Factor - pharmacology Potassium Channel Blockers Potassium Channels - physiology Streptomycin - pharmacology
ISSN:	0022-202X
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!