Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue

Considerable evidence implicates cellular senescence in the biology of aging and chronic disease. Diet and exercise are determinants of healthy aging; however, the extent to which they affect the behavior and accretion of senescent cells within distinct tissues is not clear. Here we tested the hypot...

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Vydáno v:	Diabetes (New York, N.Y.) Ročník 65; číslo 6; s. 1606
Hlavní autoři:	Schafer, Marissa J, White, Thomas A, Evans, Glenda, Tonne, Jason M, Verzosa, Grace C, Stout, Michael B, Mazula, Daniel L, Palmer, Allyson K, Baker, Darren J, Jensen, Michael D, Torbenson, Michael S, Miller, Jordan D, Ikeda, Yasuhiro, Tchkonia, Tamara, van Deursen, Jan M, Kirkland, James L, LeBrasseur, Nathan K
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.06.2016
Témata:	Adipose Tissue - cytology Aging - physiology Animals beta-Galactosidase - metabolism Body Composition Body Weight Cellular Senescence - physiology Cyclin-Dependent Kinase Inhibitor p16 - genetics Cyclin-Dependent Kinase Inhibitor p16 - metabolism Diet - adverse effects Fast Foods - adverse effects Green Fluorescent Proteins - metabolism Male Mice Mice, Transgenic Physical Conditioning, Animal - physiology
ISSN:	1939-327X, 1939-327X
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