Epigenetic Reprogramming by Somatic Cell Nuclear Transfer in Primates

We recently demonstrated that somatic cells from adult primates could be reprogrammed into a pluripotent state by somatic cell nuclear transfer. However, the low efficiency with donor cells from one monkey necessitated the need for large oocyte numbers. Here, we demonstrate nearly threefold higher b...

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Bibliographic Details
Published in:	Stem cells (Dayton, Ohio) Vol. 27; no. 6; pp. 1255 - 1264
Main Authors:	Sparman, Michelle, Dighe, Vikas, Sritanaudomchai, Hathaitip, Ma, Hong, Ramsey, Cathy, Pedersen, Darlene, Clepper, Lisa, Nighot, Prashant, Wolf, Don, Hennebold, Jon, Mitalipov, Shoukhrat
Format:	Journal Article
Language:	English
Published:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2009
Subjects:	Animals Cell Differentiation Cellular Reprogramming - genetics Embryonic stem cells Embryonic Stem Cells - cytology Epigenesis, Genetic Female Fibroblasts - cytology Gene Expression Macaca mulatta Nuclear transfer Nuclear Transfer Techniques Oocytes - cytology Pluripotent Stem Cells - cytology Primates Reprogramming Reverse Transcriptase Polymerase Chain Reaction
ISSN:	1066-5099, 1549-4918, 1549-4918
Online Access:	Get full text
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