Development of an anti-CAR antibody response in SIV-infected rhesus macaques treated with CD4-MBL CAR/CXCR5 T cells

T cells expressing a simian immunodeficiency (SIV)-specific chimeric antigen receptor (CAR) and the follicular homing molecule, CXCR5, were infused into antiretroviral therapy (ART) suppressed, SIV-infected rhesus macaques to assess their ability to localize to the lymphoid follicle and control the...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Frontiers in immunology Ročník 13; s. 1032537
Hlavní autori:	Davey, Brianna C., Pampusch, Mary S., Cartwright, Emily K., Abdelaal, Hadia M., Rakasz, Eva G., Rendahl, Aaron, Berger, Edward A., Skinner, Pamela J.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland Frontiers Media S.A 13.12.2022
Predmet:	Animals anti-drug antibodies (ADA) Antibodies - therapeutic use Antibody Formation CAR T cell CD28 Antigens HIV Immunology Immunotherapy Macaca mulatta Receptors, Chimeric Antigen rhesus macaque Simian Acquired Immunodeficiency Syndrome - therapy Simian Immunodeficiency Virus SIV SIV rhesus macaque CAR T cell HIV anti-drug antibodies (ADA) immunotherapy
ISSN:	1664-3224, 1664-3224
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!