miR-29c-3p inhibits autophagy and cisplatin resistance in ovarian cancer by regulating FOXP1/ATG14 pathway

Autophagy, characterized by the elevator of autophagy-related gene 14 (ATG14) and the dysregulation of autophagy-related proteins, contributes to the cisplatin (DDP) resistance in ovarian cancer. Forkhead box protein P1 (FOXP1), which is a well-defined transcription factor, is reported to have the o...

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Bibliographic Details
Published in:	Cell cycle (Georgetown, Tex.) Vol. 19; no. 2; pp. 193 - 206
Main Authors:	Hu, Zhenhua, Cai, Mingbo, Zhang, Ying, Tao, Lingling, Guo, Ruixia
Format:	Journal Article
Language:	English
Published:	United States Taylor & Francis 17.01.2020
Subjects:	Adaptor Proteins, Vesicular Transport - metabolism Animals ATG14 autophagy Autophagy - drug effects Autophagy - genetics Autophagy-Related Proteins - metabolism Base Sequence Cell Line, Tumor Cell Survival - drug effects Cell Survival - genetics Cisplatin - pharmacology Down-Regulation - drug effects Down-Regulation - genetics Drug Resistance, Neoplasm - drug effects Drug Resistance, Neoplasm - genetics Female Forkhead Transcription Factors - metabolism FOXP1 Gene Expression Regulation, Neoplastic - drug effects Humans Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism miR-29c-3p Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Repressor Proteins - metabolism Research Paper Signal Transduction - drug effects autophagy ATG14 miR-29c-3p FOXP1 Ovarian cancer
ISSN:	1538-4101, 1551-4005, 1551-4005
Online Access:	Get full text
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