Molecular mechanisms for ABCA1-mediated cholesterol efflux

The maintenance of cellular cholesterol homeostasis is essential for normal cell function and viability. Excessive cholesterol accumulation is detrimental to cells and serves as the molecular basis of many diseases, such as atherosclerosis, Alzheimer's disease, and diabetes mellitus. The periph...

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Bibliographic Details
Published in:	Cell cycle (Georgetown, Tex.) Vol. 21; no. 11; pp. 1121 - 1139
Main Authors:	Chen, Lei, Zhao, Zhen-Wang, Zeng, Peng-Hui, Zhou, Ying-Jie, Yin, Wen-Jun
Format:	Journal Article
Language:	English
Published:	United States Taylor & Francis 03.06.2022
Subjects:	ABCA1 apoA-I Apolipoprotein A-I - chemistry Apolipoprotein A-I - metabolism ATP Binding Cassette Transporter 1 Biological Transport cholesterol Cholesterol - metabolism Cholesterol, HDL Lipoproteins, HDL - metabolism nHDL Phosphatidylcholine-Sterol O-Acyltransferase phospholipids Review ABCA1 nHDL cholesterol phospholipids apoA-I
ISSN:	1538-4101, 1551-4005, 1551-4005
Online Access:	Get full text
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