Intracranial arterial wall imaging using three-dimensional high isotropic resolution black blood MRI at 3.0 Tesla

Purpose: To develop a high isotropic‐resolution sequence to evaluate intracranial vessels at 3.0 Tesla (T). Materials and Methods: Thirteen healthy volunteers and 4 patients with intracranial stenosis were imaged at 3.0T using 0.5‐mm isotropic‐resolution three‐dimensional (3D) Volumetric ISotropic T...

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Veröffentlicht in:Journal of magnetic resonance imaging Jg. 34; H. 1; S. 22 - 30
Hauptverfasser: Qiao, Ye, Steinman, David A., Qin, Qin, Etesami, Maryam, Schär, Michael, Astor, Brad C., Wasserman, Bruce A.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2011
Schlagworte:
Adult
Aged
Aged, 80 and over
Arteries - pathology
Brain - pathology
Cerebrospinal Fluid
Female
Fourier Analysis
Humans
Imaging, Three-Dimensional
intracranial
isotropic
Magnetic Resonance Imaging - methods
Male
Middle Aged
MRI
plaque
Reproducibility of Results
Stroke - pathology
vessel wall
ISSN:1053-1807, 1522-2586, 1522-2586
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Zusammenfassung:Purpose: To develop a high isotropic‐resolution sequence to evaluate intracranial vessels at 3.0 Tesla (T). Materials and Methods: Thirteen healthy volunteers and 4 patients with intracranial stenosis were imaged at 3.0T using 0.5‐mm isotropic‐resolution three‐dimensional (3D) Volumetric ISotropic TSE Acquisition (VISTA; TSE, turbo spin echo), with conventional 2D‐TSE for comparison. VISTA was repeated for 6 volunteers and 4 patients at 0.4‐mm isotropic‐resolution to explore the trade‐off between SNR and voxel volume. Wall signal‐to‐noise‐ratio (SNRwall), wall‐lumen contrast‐to‐noise‐ratio (CNRwall‐lumen), lumen area (LA), wall area (WA), mean wall thickness (MWT), and maximum wall thickness (maxWT) were compared between 3D‐VISTA and 2D‐TSE sequences, as well as 3D images acquired at both resolutions. Reliability was assessed by intraclass correlations (ICC). Results: Compared with 2D‐TSE measurements, 3D‐VISTA provided 58% and 74% improvement in SNRwall and CNRwall‐lumen, respectively. LA, WA, MWT and maxWT from 3D and 2D techniques highly correlated (ICCs of 0.96, 0.95, 0.96, and 0.91, respectively). CNRwall‐lumen using 0.4‐mm resolution VISTA decreased by 27%, compared with 0.5‐mm VISTA but with reduced partial‐volume‐based overestimation of wall thickness. Reliability for 3D measurements was good to excellent. Conclusion: The 3D‐VISTA provides SNR‐efficient, highly reliable measurements of intracranial vessels at high isotropic‐resolution, enabling broad coverage in a clinically acceptable time. J. Magn. Reson. Imaging 2011;. © 2011 Wiley‐Liss, Inc.
Bibliographie:ArticleID:JMRI22592
istex:AFDBBB0D2D5F8A9970D6A17B5DF63F539AF7B225
Yousem Family Research Fund
ark:/67375/WNG-5ZPL00J6-S
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1053-1807
1522-2586
1522-2586
DOI:10.1002/jmri.22592