Analysis and network representation of hotspots in protein interfaces using minimum cut trees

We propose a novel approach to analyze and visualize residue contact networks of protein interfaces by graph‐based algorithms using a minimum cut tree (mincut tree). Edges in the network are weighted according to an energy function derived from knowledge‐based potentials. The mincut tree, which is c...

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Veröffentlicht in:Proteins, structure, function, and bioinformatics Jg. 78; H. 10; S. 2283 - 2294
Hauptverfasser: Tuncbag, Nurcan, Salman, F. Sibel, Keskin, Ozlem, Gursoy, Attila
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.08.2010
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ISSN:0887-3585, 1097-0134, 1097-0134
Online-Zugang:Volltext
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