A Case of COVID-19 Pregnancy Complicated with Hydrops Fetalis and Intrauterine Death

Coronavirus disease 2019 (COVID-19) has rapidly evolved into a worldwide pandemic causing a serious global public health problem. The risk of vertical transmission of SARS-CoV-2 is still debated, and the consequences of this virus on pregnant women and their fetuses remain unknown. We report a case...

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Vydáno v:Medicina (Kaunas, Lithuania) Ročník 57; číslo 7; s. 667
Hlavní autoři: Popescu, Daniela Eugenia, Cioca, Andreea, Muresan, Cezara, Navolan, Dan, Gui, Arina, Pop, Ovidiu, Marcovici, Tamara, Ilie, Constantin, Craina, Marius, Boia, Marioara
Médium: Journal Article
Jazyk:angličtina
Vydáno: Basel MDPI AG 28.06.2021
MDPI
Témata:
Case Report
Childbirth & labor
coronavirus
Coronaviruses
COVID-19
Disease transmission
Edema
fetal death
Fetuses
Infections
Pandemics
Placenta
Pregnancy
Respiratory diseases
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Thrombosis
vertical transmission
Viral infections
Womens health
United States > US
ISSN:1648-9144, 1010-660X, 1648-9144
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Shrnutí:Coronavirus disease 2019 (COVID-19) has rapidly evolved into a worldwide pandemic causing a serious global public health problem. The risk of vertical transmission of SARS-CoV-2 is still debated, and the consequences of this virus on pregnant women and their fetuses remain unknown. We report a case of pregnancy complicated with hydrops fetalis that developed 7 weeks after recovery from a mild SARS-CoV-2 infection, leading to intrauterine death of the foetus. Evidence of SARS-CoV-2 placentitis was demonstrated by the presence of viral particles in the placenta identified by immunohistochemistry. As we excluded all possible etiological factors for non-immunologic hydrops fetalis, we believe that the fetal consequences of our case are related to vertical transmission of SARS-CoV-2 virus. To the best of our knowledge, this is the second reported case in the literature of COVID-19 infection complicated with hydrops fetalis and intrauterine fetal demise.
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ISSN:1648-9144
1010-660X
1648-9144
DOI:10.3390/medicina57070667