Spousal Cognitive Status and Risk for Declining Cognitive Function and Dementia: The Atherosclerosis Risk in Communities Study

Objectives: We investigated the relationship between the cognitive status of participants’ spouses and participants’ own cognitive outcomes, controlling for mid-life factors. Methods: Participants (n = 1845; baseline age 66–90 years) from the prospective Atherosclerosis Risk in Communities Study wer...

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Vydané v:Journal of aging and health Ročník 35; číslo 9; s. 688 - 698
Hlavní autori: Lee, Mark, Demmer, Ryan T., Kucharska-Newton, Anna, Windham, Beverly Gwen, Palta, Priya, Shippee, Tetyana, Lutsey, Pamela L.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Los Angeles, CA SAGE Publications 01.10.2023
SAGE PUBLICATIONS, INC
Predmet:
Atherosclerosis
Cognitive ability
Dementia
Health risk assessment
dementia
prospective cohort
cognitive decline
caregiving
spouse
ISSN:0898-2643, 1552-6887, 1552-6887
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Shrnutí:Objectives: We investigated the relationship between the cognitive status of participants’ spouses and participants’ own cognitive outcomes, controlling for mid-life factors. Methods: Participants (n = 1845; baseline age 66–90 years) from the prospective Atherosclerosis Risk in Communities Study were followed from 2011 to 2019. We used linear regression and Cox proportional hazard models to estimate whether spouses of people with MCI/dementia had lower cognitive functioning and elevated risk of incident dementia. Results: Having a spouse with MCI/dementia was associated with a deficit in cognitive function (b = −0.09 standard deviations; 95% CI = −0.18, 0.00). Adjustment for mid-life risk factors attenuated this association (b = −0.02 standard deviations; 95% CI = −0.10, 0.06). We observed no significant relationship between spousal MCI/dementia status and incident dementia (hazard ratio = 0.97; 95% CI = 0.69, 1.38). Discussion: Spousal cognitive status is not associated with poor cognitive outcomes independent of mid-life factors.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0898-2643
1552-6887
1552-6887
DOI:10.1177/08982643231155997