Promising zone two-stage design for a single-arm study with binary outcome

Adaptive designs are increasingly used in clinical trials to assess the effectiveness of new drugs. For a single-arm study with a binary outcome, several adaptive designs were developed by using numerical search algorithms and the conditional power approach. The design based on numerical search algo...

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Bibliographic Details

Published in:	Statistical methods in medical research Vol. 32; no. 6; p. 1159
Main Author:	Shan, Guogen
Format:	Journal Article
Language:	English
Published:	England 01.06.2023
Subjects:	Algorithms Research Design Sample Size optimal two-stage design single-arm study Adaptive design promising zone design conditional power binary response
ISSN:	1477-0334, 1477-0334
Online Access:	Get more information
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