Promising zone two-stage design for a single-arm study with binary outcome

Adaptive designs are increasingly used in clinical trials to assess the effectiveness of new drugs. For a single-arm study with a binary outcome, several adaptive designs were developed by using numerical search algorithms and the conditional power approach. The design based on numerical search algo...

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Vydáno v:	Statistical methods in medical research Ročník 32; číslo 6; s. 1159
Hlavní autor:	Shan, Guogen
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.06.2023
Témata:	Algorithms Research Design Sample Size optimal two-stage design single-arm study Adaptive design promising zone design conditional power binary response
ISSN:	1477-0334, 1477-0334
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