Crimean-Congo hemorrhagic fever: History, epidemiology, pathogenesis, clinical syndrome and genetic diversity

•Crimean–Congo hemorrhagic fever (CCHF) is the most widespread tick-borne viral disease of humans.•Its incidence in Turkey and Iran has markedly increased in the past decade.•The broad sequence diversity of the virus reflects prolonged genetic drift and reassortment between strains.•Until recently,...

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Bibliographic Details
Published in:	Antiviral research Vol. 100; no. 1; pp. 159 - 189
Main Authors:	Bente, Dennis A., Forrester, Naomi L., Watts, Douglas M., McAuley, Alexander J., Whitehouse, Chris A., Bray, Mike
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier B.V 01.10.2013 Elsevier
Subjects:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Arboviral haemorrhagic fevers Arboviroses Arbovirus Biological and medical sciences Bunyavirus Crimean–Congo hemorrhagic fever virus Genetic Variation Hemorrhagic Fever Virus, Crimean-Congo - classification Hemorrhagic Fever Virus, Crimean-Congo - genetics Hemorrhagic Fever Virus, Crimean-Congo - isolation & purification Hemorrhagic Fever Virus, Crimean-Congo - pathogenicity Hemorrhagic Fever, Crimean - diagnosis Hemorrhagic Fever, Crimean - drug therapy Hemorrhagic Fever, Crimean - epidemiology Hemorrhagic Fever, Crimean - history History, 20th Century History, 21st Century Human viral diseases Humans Infectious diseases Medical sciences Nairovirus Pharmacology. Drug treatments Phylogeny Tick-borne virus Tropical viral diseases Viral diseases Viral hemorrhagic fever Nairovirus Crimean–Congo hemorrhagic fever virus Arbovirus Viral hemorrhagic fever Bunyavirus Tick-borne virus Hemorrhagic fever Pathogenesis Congo-Crimean haemorrhagic fever History Epidemiology Case history Acari Bunyaviridae Arbovirus disease Ixodidae Public health Parasitiformes Human Crimean―Congo hemorrhagic fever virus Genetic diversity Genetic disease Infection Virus Arachnida Ixodida Arthropoda Viral disease Invertebrata Crimean-Congo hemorrhagic fever virus
ISSN:	0166-3542, 1872-9096, 1872-9096
Online Access:	Get full text
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