Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity

New diagnostics and vaccines for tuberculosis (TB) are urgently needed, but require an understanding of the requirements for protection from/susceptibility to TB. Previous studies have used unbiased approaches to determine gene signatures in single-site populations. The present study utilized a targ...

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Bibliographic Details
Published in:	Clinical microbiology and infection Vol. 20; no. 4; pp. O230 - O238
Main Authors:	Sutherland, J.S., Loxton, A.G., Haks, M.C., Kassa, D., Ambrose, L., Lee, J.-S., Ran, L., van Baarle, D., Maertzdorf, J., Howe, R., Mayanja-Kizza, H., Boom, W.H., Thiel, B.A., Crampin, A.C., Hanekom, W., Ota, M.O.C., Dockrell, H., Walzl, G., Kaufmann, S.H.E., Ottenhoff, T.H.M.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.04.2014
Subjects:	Adolescent Adult Africa South of the Sahara Biomarkers - blood Biosignature Blood Ethnicity Female Gene Expression Gene Expression Profiling HIV Infections - complications Human immunodeficiency virus Humans Lentivirus Male Middle Aged Mycobacterium Receptors, IgG - blood Retroviridae RT-MLPA tuberculosis Tuberculosis - diagnosis Young Adult Africa South of the Sahara gene expression tuberculosis Biosignature RT-MLPA
ISSN:	1198-743X, 1469-0691, 1469-0691
Online Access:	Get full text
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