Atopic Dermatitis in the Elderly Population

Atopic dermatitis is a common inflammatory disease with a chronic and relapsing course. Although considered a childhood disease, it is now evident that atopic dermatitis is also common in adulthood and in the elderly population. Atopic dermatitis typically manifests with bilateral and symmetrical ec...

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Vydáno v:Acta dermato-venereologica Ročník 103; s. adv13363
Hlavní autoři: Maurelli, Martina, Chiricozzi, Andrea, Peris, Ketty, Gisondi, Paolo, Girolomoni, Giampiero
Médium: Journal Article
Jazyk:angličtina
Vydáno: Sweden Medical Journals Sweden, on behalf of the Society for Publication of Acta Dermato-Venereologica 14.12.2023
Medical Journals Sweden
Témata:
Aged
atopic dermatitis
atopic dermatitis in elderly
Child
Comorbidity
Cost of Illness
Dermatitis, Atopic - diagnosis
Dermatitis, Atopic - drug therapy
Dermatitis, Atopic - epidemiology
elderly
Humans
older patients
Pruritus - diagnosis
Pruritus - drug therapy
Pruritus - epidemiology
Quality of Life
Review
Severity of Illness Index
treatment
ISSN:0001-5555, 1651-2057, 1651-2057
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Popis
Shrnutí:Atopic dermatitis is a common inflammatory disease with a chronic and relapsing course. Although considered a childhood disease, it is now evident that atopic dermatitis is also common in adulthood and in the elderly population. Atopic dermatitis typically manifests with bilateral and symmetrical eczematous lesions on the face, trunk and skin folds. Itch is invariably present and may be very severe, markedly  affecting daily life and sleep. In older adults, atopic dermatitis may have a high level of impact on quality of life, frequently burdening an already complex comorbid situation. The full assessment of disease burden (localizations, itch severity, sleep alterations, impact on quality of life, disease history, comorbidities) is crucial to identify the most appropriate treatment. In many cases, moderate-to-severe atopic dermatitis in the elderly population can be successfully and safely treated with biological agents inhibiting the interleukin-4/-13 pathway, whereas the use of Janus kinase inhibitors may pose concerns about the safety profile.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0001-5555
1651-2057
1651-2057
DOI:10.2340/actadv.v103.13363