Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans

Elevated plasma IL-18 is present in several conditions sharing insulin-resistance as common trait, but the association with insulin-resistance per se is not established. Plasma/serum IL-6, IL-18, TNF-α, soluble TNF receptor II (sTNFR2), and C-reactive protein (CRP) were measured in 97 patients with...

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Vydané v:	Clinical Immunology Ročník 117; číslo 2; s. 152 - 160
Hlavní autori:	Fischer, Christian P., Perstrup, Lisbeth B., Berntsen, Annika, Eskildsen, Peter, Pedersen, Bente K.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	San Diego, CA Elsevier Inc 01.11.2005 Elsevier
Predmet:	Biological and medical sciences Biomarkers - blood C-Reactive Protein - metabolism Case-Control Studies Cross-Sectional Studies Cytokines Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - metabolism Epidemiology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunopathology Inflammation Insulin resistance Insulin Resistance - physiology Interleukin-18 - blood Interleukin-6 - blood Male Medical sciences Middle Aged Obesity Receptors, Tumor Necrosis Factor, Type II - blood Tumor Necrosis Factor-alpha - metabolism Type 2 diabetes CRP SBP Type 2 diabetes Obesity OR Cytokines Inflammation Epidemiology IL-6 HDL HOMA-IR DBP TNF-α IL-18 sTNFR2 Insulin resistance TAG TZD Endocrinopathy Human Immunopathology Pancreatic hormone Cytokine Biological marker Metabolic diseases Insulin Interleukin 18 Blood plasma Target tissue resistance Immunology
ISSN:	1521-6616, 1521-7035, 1365-2567
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