Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans

Elevated plasma IL-18 is present in several conditions sharing insulin-resistance as common trait, but the association with insulin-resistance per se is not established. Plasma/serum IL-6, IL-18, TNF-α, soluble TNF receptor II (sTNFR2), and C-reactive protein (CRP) were measured in 97 patients with...

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Bibliographic Details
Published in:	Clinical Immunology Vol. 117; no. 2; pp. 152 - 160
Main Authors:	Fischer, Christian P., Perstrup, Lisbeth B., Berntsen, Annika, Eskildsen, Peter, Pedersen, Bente K.
Format:	Journal Article
Language:	English
Published:	San Diego, CA Elsevier Inc 01.11.2005 Elsevier
Subjects:	Biological and medical sciences Biomarkers - blood C-Reactive Protein - metabolism Case-Control Studies Cross-Sectional Studies Cytokines Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - metabolism Epidemiology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunopathology Inflammation Insulin resistance Insulin Resistance - physiology Interleukin-18 - blood Interleukin-6 - blood Male Medical sciences Middle Aged Obesity Receptors, Tumor Necrosis Factor, Type II - blood Tumor Necrosis Factor-alpha - metabolism Type 2 diabetes CRP SBP Type 2 diabetes Obesity OR Cytokines Inflammation Epidemiology IL-6 HDL HOMA-IR DBP TNF-α IL-18 sTNFR2 Insulin resistance TAG TZD Endocrinopathy Human Immunopathology Pancreatic hormone Cytokine Biological marker Metabolic diseases Insulin Interleukin 18 Blood plasma Target tissue resistance Immunology
ISSN:	1521-6616, 1521-7035, 1365-2567
Online Access:	Get full text
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