The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity

The interest in brown adipose tissue (BAT) as a target to combat metabolic disease has recently been renewed with the discovery of functional BAT in humans. In rodents, BAT can be activated by bile acids, which activate type 2 iodothyronine deiodinase (D2) in BAT via the G-coupled protein receptor T...

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Bibliographic Details
Published in:	Cell metabolism Vol. 22; no. 3; p. 418
Main Authors:	Broeders, Evie P M, Nascimento, Emmani B M, Havekes, Bas, Brans, Boudewijn, Roumans, Kay H M, Tailleux, Anne, Schaart, Gert, Kouach, Mostafa, Charton, Julie, Deprez, Benoit, Bouvy, Nicole D, Mottaghy, Felix, Staels, Bart, van Marken Lichtenbelt, Wouter D, Schrauwen, Patrick
Format:	Journal Article
Language:	English
Published:	United States 01.09.2015
Subjects:	Adipocytes, Brown - drug effects Adipocytes, Brown - metabolism Adipose Tissue, Brown - drug effects Adipose Tissue, Brown - metabolism Administration, Oral Adult Cells, Cultured Chenodeoxycholic Acid - administration & dosage Chenodeoxycholic Acid - blood Chenodeoxycholic Acid - pharmacology Energy Metabolism - drug effects Female Humans Receptors, G-Protein-Coupled - metabolism Signal Transduction - drug effects Young Adult
ISSN:	1932-7420, 1932-7420
Online Access:	Get more information
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