Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication

Liver fibrosis is a strong predictor of long-term mortality in individuals with metabolic-associated fatty liver disease; yet, the mechanisms underlying the progression from the comparatively benign fatty liver state to advanced non-alcoholic steatohepatitis (NASH) and liver fibrosis are incompletel...

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Vydané v:	Cell metabolism Ročník 33; číslo 8; s. 1685
Hlavní autori:	Loft, Anne, Alfaro, Ana Jimena, Schmidt, Søren Fisker, Pedersen, Felix Boel, Terkelsen, Mike Krogh, Puglia, Michele, Chow, Kan Kau, Feuchtinger, Annette, Troullinaki, Maria, Maida, Adriano, Wolff, Gretchen, Sakurai, Minako, Berutti, Riccardo, Ekim Üstünel, Bilgen, Nawroth, Peter, Ravnskjaer, Kim, Diaz, Mauricio Berriel, Blagoev, Blagoy, Herzig, Stephan
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 03.08.2021
Predmet:	Communication Gene Regulatory Networks Hepatocytes - metabolism Humans Liver - metabolism Liver Cirrhosis - metabolism Non-alcoholic Fatty Liver Disease - metabolism nonalcoholic steatohepatitis genomic reprogramming liver fibrosis ELF3 Cell type-specific profiling transcription factor networks metabolic-associated fatty liver disease hepatocytes GLIS2
ISSN:	1932-7420, 1932-7420
On-line prístup:	Zistit podrobnosti o prístupe
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