Oxidative stress pathways involved in cytotoxicity and genotoxicity of titanium dioxide (TiO2) nanoparticles on cells constitutive of alveolo-capillary barrier in vitro

The health risks of nanoparticles remain a serious concern given their prevalence from industrial and domestic use. The primary route of titanium dioxide nanoparticle exposure is inhalation. The extent to which nanoparticles contribute to cellular toxicity is known to associate induction of oxidativ...

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Bibliographic Details
Published in:	Toxicology in vitro Vol. 33; pp. 125 - 135
Main Authors:	Hanot-Roy, Maïté, Tubeuf, Emilie, Guilbert, Ariane, Bado-Nilles, Anne, Vigneron, Pascale, Trouiller, Bénédicte, Braun, Anne, Lacroix, Ghislaine
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.06.2016 Elsevier
Subjects:	Apoptosis - drug effects Capillaries Cell Cycle Checkpoints - drug effects Cell death Cell Line Cell Line, Tumor Cell Survival - drug effects DNA Damage DNA repair Ecotoxicology Glutathione - metabolism Histones - metabolism HSP27 Heat-Shock Proteins - metabolism Humans Life Sciences Metal Nanoparticles - toxicity Nanotoxicology Oxidative stress Oxidative Stress - drug effects p38 Mitogen-Activated Protein Kinases - metabolism Pulmonary Alveoli Reactive Oxygen Species - metabolism Titanium - toxicity Toxicology Oxidative stress Nanotoxicology Cell death DNA repair DNA REPAIR CELL DEATH OXIDATIVE STRESS NANOTOXICOLOGY
ISSN:	0887-2333, 1879-3177, 1879-3177
Online Access:	Get full text
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