Changing varicella epidemiology in active surveillance sites--United States, 1995-2005

Significant reductions in varicella incidence were reported from 1995 to 2000 in the varicella active surveillance sites of Antelope Valley (AV), California, and West Philadelphia (WP), Pennsylvania. We examined incidence rates, median age, and vaccination status of case patients for 1995-2005. Cove...

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Bibliographic Details
Published in:The Journal of infectious diseases Vol. 197 Suppl 2; p. S71
Main Authors: Guris, Dalya, Jumaan, Aisha O, Mascola, Laurene, Watson, Barbara M, Zhang, John X, Chaves, Sandra S, Gargiullo, Paul, Perella, Dana, Civen, Rachel, Seward, Jane F
Format: Journal Article
Language:English
Published: United States 01.03.2008
Subjects:
Adolescent
Adult
California - epidemiology
Chickenpox - epidemiology
Chickenpox - prevention & control
Chickenpox Vaccine - administration & dosage
Child
Child, Preschool
Humans
Immunization Programs
Incidence
Infant
Pennsylvania - epidemiology
Population Surveillance - methods
United States - epidemiology
United States
California
Pennsylvania
ISSN:0022-1899
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Summary:Significant reductions in varicella incidence were reported from 1995 to 2000 in the varicella active surveillance sites of Antelope Valley (AV), California, and West Philadelphia (WP), Pennsylvania. We examined incidence rates, median age, and vaccination status of case patients for 1995-2005. Coverage data were from the National Immunization Survey. By 2005, coverage among children 19-35 months of age reached 92% (AV) and 94% (WP); 57% and 64% of case patients in AV and WP, respectively, were vaccinated; and varicella incidence declined by 89.8% in AV and 90.4% in WP. Incidence declined in all age groups, especially among children <10 years of age in both sites and among adolescents 10-14 years of age in WP. In AV, since 2000, the incidence among adolescents 10-14 and 15-19 years of age increased. Implementation of school requirements through 10th grade in WP may explain the differences in the decline in incidence among adolescents. Continued surveillance will be important to monitor the impact that the 2-dose vaccine policy in children has on varicella epidemiology.
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ISSN:0022-1899
DOI:10.1086/522156