Cohort Profile Update: Reflecting back and looking ahead: Updating the Comparative Outcomes and Service Utilization Trends (COAST) Study to include 28 years of linked data from people with and without HIV in British Columbia, Canada

IntroductionThe Comparative Outcomes and Service Utilization Trends (COAST) study compares health outcomes among People With HIV (PWH) and People Without HIV (PWoH) in British Columbia (BC), Canada. The cohort was recently updated to include persons diagnosed with HIV after March 31, 2013, and expan...

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Vydané v:International journal of population data science Ročník 10; číslo 1; s. 2496
Hlavní autori: Budu, Michael Owusu, Kooij, Katherine W., Heath, Katherine, McLinden, Taylor, Cardinal, Claudette, Emerson, Scott D., Sereda, Paul, Trigg, Jason, Li, Jenny, Ding, Erin, Hull, Mark W., Salters, Kate, Lima, Viviane D., Barrios, Rolando, Montaner, Julio S. G., Hogg, Robert S., COAST Study Team
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Wales Swansea University 01.01.2025
Predmet:
Administrative Data; Data Linkage; Public Health
Adolescent
Adult
Aged
Ageing
British Columbia - epidemiology
Chronic Disease - epidemiology
Cohort Studies
Female
healthcare use
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV research
Humans
Longitudinal cohort studies
Male
Middle Aged
Patient Acceptance of Health Care - statistics & numerical data
Population Data Science
Registries
Substance-Related Disorders - epidemiology
Young Adult
British Columbia
ageing
population health
HIV
healthcare use
data linkage
HIV research
administrative data
public health
longitudinal cohort studies
ISSN:2399-4908, 2399-4908
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Shrnutí:IntroductionThe Comparative Outcomes and Service Utilization Trends (COAST) study compares health outcomes among People With HIV (PWH) and People Without HIV (PWoH) in British Columbia (BC), Canada. The cohort was recently updated to include persons diagnosed with HIV after March 31, 2013, and expanded to broaden research applications. MethodsCOAST includes PWH and a 10% random sample of the general population without HIV, all aged ≥19. Our study links an HIV registry to healthcare practitioner billing, hospital and emergency department attendance data, prescription drug dispensations, and a cancer registry. Our cohort update included new sampling strategies, adding data on emergency department visits not previously captured, and extending our follow-up period to 28 years (from 1992 to 2020). COAST now includes 17,119 PWH and 615,264 PWoH. Findings to dateCOAST has contributed to our understanding of combination antiretroviral therapy (ART) use, health service utilization, chronic diseases, mental health and substance use disorders, and mortality among PWH in BC. Key findings include earlier age at diagnosis of certain chronic conditions, a higher incidence of mood disorders among PWH, and noteworthy shifts in causes of death among PWH on ART. The updated cohort will provide insights into the changing nature of the population living with HIV in BC and serves as a novel foundation for further research. Future plansTo explore and extend knowledge of the evolving trends among people living and aging with HIV in BC, regular data linkage updates and the inclusion of additional datasets are scheduled every two years.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
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Conflicts of Interests: All authors have no conflicts of interest to declare.
ISSN:2399-4908
2399-4908
DOI:10.23889/ijpds.v10i1.2496