The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

Fibroblast growth factor 21 (FGF21) is a recently discovered metabolic regulator. Exogenous FGF21 produces beneficial metabolic effects in animal models; however, the translation of these observations to humans has not been tested. Here, we studied the effects of LY2405319 (LY), a variant of FGF21,...

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Vydané v:	Cell metabolism Ročník 18; číslo 3; s. 333
Hlavní autori:	Gaich, Gregory, Chien, Jenny Y, Fu, Haoda, Glass, Leonard C, Deeg, Mark A, Holland, William L, Kharitonenkov, Alexei, Bumol, Thomas, Schilske, Holger K, Moller, David E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 03.09.2013
Predmet:	Adiponectin - blood Adolescent Adult Aged Blood Glucose - analysis Body Mass Index Body Weight Cholesterol, HDL - blood Cholesterol, LDL - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Double-Blind Method Dyslipidemias - complications Dyslipidemias - drug therapy Female Fibroblast Growth Factors - therapeutic use Humans Insulin - blood Male Middle Aged Obesity - complications Obesity - drug therapy Placebo Effect Triglycerides - blood Young Adult
ISSN:	1932-7420, 1932-7420
On-line prístup:	Zistit podrobnosti o prístupe
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