Coexisting Liquid Phases Underlie Nucleolar Subcompartments

The nucleolus and other ribonucleoprotein (RNP) bodies are membrane-less organelles that appear to assemble through phase separation of their molecular components. However, many such RNP bodies contain internal subcompartments, and the mechanism of their formation remains unclear. Here, we combine i...

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Vydané v:	Cell Ročník 165; číslo 7; s. 1686 - 1697
Hlavní autori:	Feric, Marina, Vaidya, Nilesh, Harmon, Tyler S, Mitrea, Diana M, Zhu, Lian, Richardson, Tiffany M, Kriwacki, Richard W, Pappu, Rohit V, Brangwynne, Clifford P
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 16.06.2016
Predmet:	Animals Caenorhabditis elegans Cell Nucleolus - chemistry Cells, Cultured Chromosomal Proteins, Non-Histone - analysis Intestines - chemistry Intestines - cytology Mammals Nuclear Proteins - analysis Oocytes - chemistry Oocytes - cytology Ribonucleoproteins - metabolism RNA Processing, Post-Transcriptional Xenopus laevis
ISSN:	1097-4172
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