Electrocardiographic characteristics before and after correction of right-sided congenital heart defects in children and its relation to prognosis
Congenital heart defects are the most common birth defects and occur in 0.8% of all live births. Nowadays, patients with congenital heart defects usually survive with many event-free years despite abnormal cardiac hemodynamics. However, most patients still need life-long follow-up and main factors f...
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| Veröffentlicht in: | Journal of electrocardiology Jg. 52; S. 53 - 58 |
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01.01.2019
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| Abstract | Congenital heart defects are the most common birth defects and occur in 0.8% of all live births. Nowadays, patients with congenital heart defects usually survive with many event-free years despite abnormal cardiac hemodynamics. However, most patients still need life-long follow-up and main factors for morbidity and mortality in these patients are cardiac failure, arrhythmias or pulmonary hypertension (PH) [1], The electrocardiogram (ECG) is a noninvasive, widely-used, inexpensive tool that can be used during long-term follow-up of these patients, particularly in order to help predict occurrence of rhythm disorders and sudden cardiac death. From birth to adulthood, several physiological changes influence the cardiac electrical activity. These encompass postnatal circulatory changes and changes due to growth of the body including the heart. Due to the rapid structural and functional changes throughout childhood, interpretation of ECGs in pediatric patients is more challenging than in adults and normal values are always needed for the interpretation of the pediatric ECG. In contrast to adult cardiology, in pediatric cardiology, many congenital heart defects affect the right side of the heart. In this review, we will focus on the ECG of pediatric patients with the most frequent right-sided congenital heart defects: ostium secundum atrial septal defect (ASDII), tetralogy of Fallot (ToF) and pulmonary stenosis (PS). |
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| AbstractList | Congenital heart defects are the most common birth defects and occur in 0.8% of all live births. Nowadays, patients with congenital heart defects usually survive with many event-free years despite abnormal cardiac hemodynamics. However, most patients still need life-long follow-up and main factors for morbidity and mortality in these patients are cardiac failure, arrhythmias or pulmonary hypertension (PH) [1], The electrocardiogram (ECG) is a noninvasive, widely-used, inexpensive tool that can be used during long-term follow-up of these patients, particularly in order to help predict occurrence of rhythm disorders and sudden cardiac death. From birth to adulthood, several physiological changes influence the cardiac electrical activity. These encompass postnatal circulatory changes and changes due to growth of the body including the heart. Due to the rapid structural and functional changes throughout childhood, interpretation of ECGs in pediatric patients is more challenging than in adults and normal values are always needed for the interpretation of the pediatric ECG. In contrast to adult cardiology, in pediatric cardiology, many congenital heart defects affect the right side of the heart. In this review, we will focus on the ECG of pediatric patients with the most frequent right-sided congenital heart defects: ostium secundum atrial septal defect (ASDII), tetralogy of Fallot (ToF) and pulmonary stenosis (PS). |
| Author | Nassif, Martina Blom, Nico A. ten Harkel, Arend D.J. Kamphuis, Vivian P. Swenne, Cees A. Raad, Daphne |
| Author_xml | – sequence: 1 givenname: Vivian P. surname: Kamphuis fullname: Kamphuis, Vivian P. email: v.p.kamphuis@lumc.nl organization: Department of Pediatrics, Division of Pediatric Cardiology, Leiden University Medical Center, Leiden, the Netherlands – sequence: 2 givenname: Daphne surname: Raad fullname: Raad, Daphne organization: Department of Pediatrics, Division of Pediatric Cardiology, Leiden University Medical Center, Leiden, the Netherlands – sequence: 3 givenname: Martina surname: Nassif fullname: Nassif, Martina organization: Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands – sequence: 4 givenname: Cees A. surname: Swenne fullname: Swenne, Cees A. organization: Department of Pediatrics, Division of Pediatric Cardiology, Academic Medical Center, Amsterdam, the Netherlands – sequence: 5 givenname: Nico A. surname: Blom fullname: Blom, Nico A. organization: Department of Pediatrics, Division of Pediatric Cardiology, Leiden University Medical Center, Leiden, the Netherlands – sequence: 6 givenname: Arend D.J. surname: ten Harkel fullname: ten Harkel, Arend D.J. organization: Department of Pediatrics, Division of Pediatric Cardiology, Leiden University Medical Center, Leiden, the Netherlands |
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| Cites_doi | 10.1136/hrt.14.2.193 10.1046/j.1540-8167.2005.40312.x 10.1111/anec.12104 10.1053/euhj.2000.2399 10.1136/hrt.12.3.277 10.1016/j.jacc.2007.05.040 10.1016/0735-1097(95)00554-4 10.1007/s12325-008-0081-3 10.1161/01.CIR.28.5.893 10.1007/s00246-015-1119-3 10.1161/01.CIR.59.6.1241 10.1161/01.CIR.28.3.362 10.1016/j.ijcard.2007.02.009 10.1161/CIRCULATIONAHA.107.688770 10.1111/j.1540-8167.1997.tb01031.x 10.1016/S0022-0736(82)80039-3 10.1038/ng.517 10.1017/S1047951104004020 10.1161/01.CIR.95.2.401 10.1161/01.CIR.54.2.289 |
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tetralogy of Fallot children publication-title: J Cardiovasc Electrophysiol doi: 10.1111/j.1540-8167.1997.tb01031.x – volume: 15 start-page: 9 year: 1982 ident: 10.1016/j.jelectrocard.2018.10.001_bb0050 article-title: Influence of age on atrioventricular conduction intervals in children with and without atrial septal defect publication-title: J Electrocardiol doi: 10.1016/S0022-0736(82)80039-3 – volume: 42 start-page: 153 year: 2010 ident: 10.1016/j.jelectrocard.2018.10.001_bb0040 article-title: Genome-wide association study of PR interval publication-title: Nat Genet doi: 10.1038/ng.517 – volume: 14 start-page: 360 year: 2004 ident: 10.1016/j.jelectrocard.2018.10.001_bb0070 article-title: Time course of appearance of markers of arrhythmia in patients with tetralogy of Fallot before and after surgery publication-title: Cardiol Young doi: 10.1017/S1047951104004020 – volume: 95 start-page: 401 year: 1997 ident: 10.1016/j.jelectrocard.2018.10.001_bb0090 article-title: Depolarization-repolarization inhomogeneity after repair of tetralogy of Fallot. The substrate for malignant ventricular tachycardia? publication-title: Circulation doi: 10.1161/01.CIR.95.2.401 – volume: 54 start-page: 289 year: 1976 ident: 10.1016/j.jelectrocard.2018.10.001_bb0095 article-title: Sudden death among postoperative patients with tetralogy of Fallot: a follow-up study of 243 patients for an average of twelve years publication-title: Circulation doi: 10.1161/01.CIR.54.2.289 |
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| SubjectTerms | Blood Blood clots Cardiovascular Child Child, Preschool Coronary vessels Electrocardiography Female Heart Defects, Congenital - physiopathology Heart Defects, Congenital - surgery Heart failure Hematology Hemodynamics Humans Infant Male Prognosis |
| Title | Electrocardiographic characteristics before and after correction of right-sided congenital heart defects in children and its relation to prognosis |
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