Pro- and Anti-Inflammatory Responses in Severe COVID-19-Induced Acute Respiratory Distress Syndrome—An Observational Pilot Study

The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by the immune response. First studies indicate altered lymphocyte counts and function. However, interactions of pro- and anti-inflammatory mechanisms remain elusive. In the current study we characterized the immune responses i...

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Vydané v:	Frontiers in immunology Ročník 11; s. 581338
Hlavní autori:	Notz, Quirin, Schmalzing, Marc, Wedekink, Florian, Schlesinger, Tobias, Gernert, Michael, Herrmann, Johannes, Sorger, Lena, Weismann, Dirk, Schmid, Benedikt, Sitter, Magdalena, Schlegel, Nicolas, Kranke, Peter, Wischhusen, Jörg, Meybohm, Patrick, Lotz, Christopher
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland Frontiers Media S.A 06.10.2020
Predmet:	acute respiratory distress syndrome Aged Antibodies, Viral - blood Antibodies, Viral - immunology Betacoronavirus - immunology Coronavirus Disease 2019 Coronavirus Infections - immunology Coronavirus Infections - pathology COVID-19 Cytokine Release Syndrome - immunology Cytokine Release Syndrome - pathology cytokines Female growth differentiation factor 15 Growth Differentiation Factor 15 - blood Humans Immunoglobulin G - blood Immunoglobulin G - immunology Immunology inflammation Intensive Care Units Interleukin-10 - blood Interleukin-6 - blood Longitudinal Studies Lymphopenia Male Middle Aged Pandemics Pilot Projects Pneumonia, Viral - immunology Pneumonia, Viral - pathology Retrospective Studies SARS-CoV-2 Severe Acute Respiratory Syndrome - immunology Severe Acute Respiratory Syndrome - pathology Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein, Coronavirus - immunology Coronavirus Disease 2019 immune response inflammation Severe Acute Respiratory Syndrome Coronavirus 2 acute respiratory distress syndrome cytokines growth differentiation factor 15
ISSN:	1664-3224, 1664-3224
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