Discovery of novel eGFR-associated multiple independent signals using a quasi-adaptive method

A decreased estimated glomerular filtration rate (eGFR) leading to chronic kidney disease is a significant public health problem. Kidney function is a heritable trait, and recent application of genome-wide association studies (GWAS) successfully identified multiple eGFR-associated genetic loci. To i...

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Veröffentlicht in:	Frontiers in genetics Jg. 13; S. 997302
Hauptverfasser:	Ghasemi, Sahar, Becker, Tim, Grabe, Hans J., Teumer, Alexander
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 31.10.2022
Schlagworte:	colocalization conditional association analysis estimated glomerular filtration rate (eGFR) expression quantitative trait loci (eQTL) Genetics genome-wide association studies (GWAS) SNP-specific alpha-level expression quantitative trait loci (eQTL) SNP-specific alpha-level genome-wide association studies (GWAS) colocalization conditional association analysis estimated glomerular filtration rate (eGFR)
ISSN:	1664-8021, 1664-8021
Online-Zugang:	Volltext
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