Discovery of novel eGFR-associated multiple independent signals using a quasi-adaptive method

A decreased estimated glomerular filtration rate (eGFR) leading to chronic kidney disease is a significant public health problem. Kidney function is a heritable trait, and recent application of genome-wide association studies (GWAS) successfully identified multiple eGFR-associated genetic loci. To i...

Celý popis

Podrobná bibliografie

Vydáno v:	Frontiers in genetics Ročník 13; s. 997302
Hlavní autoři:	Ghasemi, Sahar, Becker, Tim, Grabe, Hans J., Teumer, Alexander
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland Frontiers Media S.A 31.10.2022
Témata:	colocalization conditional association analysis estimated glomerular filtration rate (eGFR) expression quantitative trait loci (eQTL) Genetics genome-wide association studies (GWAS) SNP-specific alpha-level expression quantitative trait loci (eQTL) SNP-specific alpha-level genome-wide association studies (GWAS) colocalization conditional association analysis estimated glomerular filtration rate (eGFR)
ISSN:	1664-8021, 1664-8021
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!