Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate

The risk of type 2 diabetes is inversely correlated with plasma concentrations of odd-chain fatty acids [OCFAs; pentadecanoic acid (15:0) and heptadecanoic acid (17:0)], which are considered as biomarkers for dairy fat intake in humans. However, rodent studies suggest that OCFAs are synthesized endo...

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Bibliographic Details
Published in:	The American journal of clinical nutrition Vol. 105; no. 6; p. 1544
Main Authors:	Weitkunat, Karolin, Schumann, Sara, Nickel, Daniela, Hornemann, Silke, Petzke, Klaus J, Schulze, Matthias B, Pfeiffer, Andreas Fh, Klaus, Susanne
Format:	Journal Article
Language:	English
Published:	United States 01.06.2017
Subjects:	Adult Biomarkers - blood Cell Line, Tumor Cellulose - pharmacology Cross-Over Studies Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - prevention & control Dietary Fiber - metabolism Dietary Fiber - pharmacology Dietary Fiber - therapeutic use Double-Blind Method Fatty Acids - biosynthesis Fatty Acids - blood Female Humans Inulin - pharmacology Inulin - therapeutic use Liver - drug effects Liver - metabolism Male Middle Aged Phospholipids - blood Propionates - metabolism Propionates - pharmacology short-chain fatty acid long-chain fatty acid heptadecanoic liver pentadecanoic fermentation biomarker phospholipid propionyl-CoA soluble fiber
ISSN:	1938-3207, 1938-3207
Online Access:	Get more information
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