Mitochondrial Genome Study Identifies Association Between Primary Open-Angle Glaucoma and Variants in MT-CYB, MT-ND4 Genes and Haplogroups

Background and purpose: Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by death of retinal ganglion cells and atrophy of the optic nerve head. The susceptibility of the optic nerve to damage has been shown to be mediated by mitochondrial dysfunction. In this study, we aimed...

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Bibliographic Details

Published in:	Frontiers in genetics Vol. 12; p. 781189
Main Authors:	Lo Faro, Valeria, Nolte, Ilja M., Ten Brink, Jacoline B., Snieder, Harold, Jansonius, Nomdo M., Bergen, Arthur A., Lifelines Cohort Study
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 16.12.2021
Subjects:	Genetics haplogroup K mitochondrial haplogroup mitochondrial polymorphism MT-CYB MT-ND4 primary open-angle glaucoma (POAG) MT-ND4 haplogroup K primary open-angle glaucoma (POAG) mitochondrial haplogroup MT-CYB mitochondrial polymorphism genetic association study
ISSN:	1664-8021, 1664-8021
Online Access:	Get full text
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