The 2000HIV study: Design, multi-omics methods and participant characteristics

Even during long-term combination antiretroviral therapy (cART), people living with HIV (PLHIV) have a dysregulated immune system, characterized by persistent immune activation, accelerated immune ageing and increased risk of non-AIDS comorbidities. A multi-omics approach is applied to a large cohor...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 13; p. 982746
Main Authors:	Vos, Wilhelm A. J. W., Groenendijk, Albert L., Blaauw, Marc J. T., van Eekeren, Louise E., Navas, Adriana, Cleophas, Maartje C. P., Vadaq, Nadira, Matzaraki, Vasiliki, dos Santos, Jéssica C., Meeder, Elise M. G., Fröberg, Janeri, Weijers, Gert, Zhang, Yue, Fu, Jingyuan, ter Horst, Rob, Bock, Christoph, Knoll, Rainer, Aschenbrenner, Anna C., Schultze, Joachim, Vanderkerckhove, Linos, Hwandih, Talent, Wonderlich, Elizabeth R., Vemula, Sai V., van der Kolk, Mike, de Vet, Sterre C. P., Blok, Willem L., Brinkman, Kees, Rokx, Casper, Schellekens, Arnt F. A., de Mast, Quirijn, Joosten, Leo A. B., Berrevoets, Marvin A. H., Stalenhoef, Janneke E., Verbon, Annelies, van Lunzen, Jan, Netea, Mihai G., van der Ven, Andre J. A. M.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 20.12.2022
Subjects:	cardiovascular disease Carotid Intima-Media Thickness COVID-19 COVID-19 Vaccines - therapeutic use Female hepatic disease HIV Infections - drug therapy HIV Infections - epidemiology HIV-1 Homosexuality, Male Humans Immunology Longitudinal Studies Male multi-omics Multiomics non-AIDS comorbidities Prospective Studies Sexual and Gender Minorities COVID-19 HIV-1 cardiovascular disease HIV extreme phenotype multi-omics HIV reservoir non-AIDS comorbidities hepatic disease
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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