Isolated thrombocytosis with BCR::ABL1 gene rearrangement – a distinct entity or a variant of chronic myelogenous leukemia (CML)? Case report and review of literature

•Isolated thrombocytosis with BCR::ABL1 is rare.•Most cases are asymptomatic.•BCR::ABL1 gene rearrangement is confined to megakaryocytes.•qPCR is most efficient in diagnosis of BCR::ABL1 gene rearrangement.•Timely diagnosis is vital for targeted therapy. Chronic myeloid leukemia (CML) with isolated...

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Bibliographic Details

Published in:	Human Pathology Reports Vol. 41; p. 300785
Main Authors:	Prajapati, Vipulkumar, Flores, Raina R., Nooruddin, Zohra I., Medina, Edward A., Purnell, Gabriel, Ehman, William, Rodriguez, Juana, Kane, Sheila, Ortega, Veronica, Velagaleti, Gopalrao V.N.
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01.09.2025 Elsevier
Subjects:	FISH Isolated thrombocytosis with BCR::ABL1 gene rearrangement Megakaryocytes Pathology qPCR FISH qPCR Megakaryocytes Isolated thrombocytosis with BCR::ABL1 gene rearrangement
ISSN:	2772-736X, 2772-736X
Online Access:	Get full text
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