An Image Analysis Pipeline for Quantifying the Features of Fluorescently-Labeled Biomolecular Condensates in Cells

Biomolecular condensates are cellular organelles formed through liquid-liquid phase separation (LLPS) that play critical roles in cellular functions including signaling, transcription, translation, and stress response. Importantly, condensate misregulation is associated with human diseases, includin...

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Veröffentlicht in:	Frontiers in bioinformatics Jg. 2; S. 897238
Hauptverfasser:	Baggett, David W., Medyukhina, Anna, Tripathi, Swarnendu, Shirnekhi, Hazheen K., Wu, Huiyun, Pounds, Stanley B., Khairy, Khaled, Kriwacki, Richard
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 06.06.2022
Schlagworte:	Bioinformatics biomolecular condensate fluorescence microscopy image analysis liquid-liquid phase separation open-source software puncta features biomolecular condensate open-source software liquid-liquid phase separation fluorescence microscopy image analysis puncta features
ISSN:	2673-7647, 2673-7647
Online-Zugang:	Volltext
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