Gut microbiota mediates the protective role of Lactobacillus plantarum in ameliorating deoxynivalenol-induced apoptosis and intestinal inflammation of broiler chickens

The protection of Lactobacillus plantarum JM113 against deoxynivalenol (DON)-induced apoptosis and intestinal inflammation on the jejunum of broiler chickens and the potential roles of gut microbiota were determined. A total of 144 one-day-old male broilers (Arbor Acres) were randomly divided into 3...

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Bibliographic Details
Published in:	Poultry science Vol. 99; no. 5; pp. 2395 - 2406
Main Authors:	Yang, Xin, Liang, Saisai, Guo, Fangshen, Ren, Zhouzheng, Yang, Xiaojun, Long, Fangyu
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 01.05.2020 Elsevier
Subjects:	Anaeroplasma Animals Antioxidants - metabolism apoptosis Apoptosis - drug effects B-cell lymphoma bacterial communities Bacteroidetes broiler chicken broiler chickens cell proliferation Chickens - physiology community structure deoxynivalenol diet dysbiosis fatty acid composition Gastrointestinal Microbiome - drug effects gene expression genes gut microbiota Immunity, Mucosal - drug effects Immunologic Factors - administration & dosage Immunology, Health and Disease In Vitro Techniques inflammation Inflammation - chemically induced Inflammation - immunology Inflammation - prevention & control Inflammation - veterinary Intestinal Diseases - chemically induced Intestinal Diseases - immunology Intestinal Diseases - prevention & control Intestinal Diseases - veterinary intestinal inflammation intestinal microorganisms Intestinal Mucosa - immunology jejunum Lactobacillus Lactobacillus plantarum Lactobacillus plantarum - chemistry Lipopolysaccharides - adverse effects Male males messenger RNA mucosa Poultry Diseases - chemically induced Poultry Diseases - immunology Poultry Diseases - prevention & control propionic acid Protective Agents - administration & dosage protective effect rapamycin short chain fatty acids Spleen - drug effects Toll-like receptor 2 Trichothecenes - toxicity deoxynivalenol intestinal inflammation broiler chicken gut microbiota Lactobacillus
ISSN:	0032-5791, 1525-3171, 1525-3171
Online Access:	Get full text
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