The podocyte slit diaphragm—from a thin grey line to a complex signalling hub

This article highlights the evolution in understanding of the podocyte slit diaphragm. Now appreciated as far more than a simple intercellular connection, the slit diaphragm controls the structure and function of the glomerular filtration barrier. However, several slit diaphragm properties remain un...

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Bibliographic Details
Published in:	Nature reviews. Nephrology Vol. 9; no. 10; pp. 587 - 598
Main Authors:	Grahammer, Florian, Schell, Christoph, Huber, Tobias B.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.10.2013 Nature Publishing Group
Subjects:	692/698/272/1684/1587/2101 692/699/1585/2759 Animals Biology Care and treatment Cytoskeleton Diagnosis Disease Endothelium Glomerular Filtration Barrier - metabolism Humans Intercellular Junctions - metabolism Kidney glomerulus Kidneys Medicine Medicine & Public Health Mutation Nephrology Nephrotic syndrome Phosphorylation Physiological aspects Podocytes - metabolism Proteins Renal Insufficiency, Chronic - metabolism review-article Signal Transduction - physiology Transmission electron microscopy Urine Germany
ISSN:	1759-5061, 1759-507X, 1759-507X
Online Access:	Get full text
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