Iterative-Trained Semi-Blind Deconvolution Algorithm to Compensate Straylight in Retinal Images

The optical quality of an image depends on both the optical properties of the imaging system and the physical properties of the medium in which the light travels from the object to the final imaging sensor. The analysis of the point spread function of the optical system is an objective way to quanti...

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Veröffentlicht in:Journal of imaging Jg. 7; H. 4; S. 73
Hauptverfasser: Ávila, Francisco J., Ares, Jorge, Marcellán, María C., Collados, María V., Remón, Laura
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Basel MDPI AG 16.04.2021
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Abstract The optical quality of an image depends on both the optical properties of the imaging system and the physical properties of the medium in which the light travels from the object to the final imaging sensor. The analysis of the point spread function of the optical system is an objective way to quantify the image degradation. In retinal imaging, the presence of corneal or cristalline lens opacifications spread the light at wide angular distributions. If the mathematical operator that degrades the image is known, the image can be restored through deconvolution methods. In the particular case of retinal imaging, this operator may be unknown (or partially) due to the presence of cataracts, corneal edema, or vitreous opacification. In those cases, blind deconvolution theory provides useful results to restore important spatial information of the image. In this work, a new semi-blind deconvolution method has been developed by training an iterative process with the Glare Spread Function kernel based on the Richardson-Lucy deconvolution algorithm to compensate a veiling glare effect in retinal images due to intraocular straylight. The method was first tested with simulated retinal images generated from a straylight eye model and applied to a real retinal image dataset composed of healthy subjects and patients with glaucoma and diabetic retinopathy. Results showed the capacity of the algorithm to detect and compensate the veiling glare degradation and improving the image sharpness up to 1000% in the case of healthy subjects and up to 700% in the pathological retinal images. This image quality improvement allows performing image segmentation processing with restored hidden spatial information after deconvolution.
AbstractList The optical quality of an image depends on both the optical properties of the imaging system and the physical properties of the medium in which the light travels from the object to the final imaging sensor. The analysis of the point spread function of the optical system is an objective way to quantify the image degradation. In retinal imaging, the presence of corneal or cristalline lens opacifications spread the light at wide angular distributions. If the mathematical operator that degrades the image is known, the image can be restored through deconvolution methods. In the particular case of retinal imaging, this operator may be unknown (or partially) due to the presence of cataracts, corneal edema, or vitreous opacification. In those cases, blind deconvolution theory provides useful results to restore important spatial information of the image. In this work, a new semi-blind deconvolution method has been developed by training an iterative process with the Glare Spread Function kernel based on the Richardson-Lucy deconvolution algorithm to compensate a veiling glare effect in retinal images due to intraocular straylight. The method was first tested with simulated retinal images generated from a straylight eye model and applied to a real retinal image dataset composed of healthy subjects and patients with glaucoma and diabetic retinopathy. Results showed the capacity of the algorithm to detect and compensate the veiling glare degradation and improving the image sharpness up to 1000% in the case of healthy subjects and up to 700% in the pathological retinal images. This image quality improvement allows performing image segmentation processing with restored hidden spatial information after deconvolution.
The optical quality of an image depends on both the optical properties of the imaging system and the physical properties of the medium in which the light travels from the object to the final imaging sensor. The analysis of the point spread function of the optical system is an objective way to quantify the image degradation. In retinal imaging, the presence of corneal or cristalline lens opacifications spread the light at wide angular distributions. If the mathematical operator that degrades the image is known, the image can be restored through deconvolution methods. In the particular case of retinal imaging, this operator may be unknown (or partially) due to the presence of cataracts, corneal edema, or vitreous opacification. In those cases, blind deconvolution theory provides useful results to restore important spatial information of the image. In this work, a new semi-blind deconvolution method has been developed by training an iterative process with the Glare Spread Function kernel based on the Richardson-Lucy deconvolution algorithm to compensate a veiling glare effect in retinal images due to intraocular straylight. The method was first tested with simulated retinal images generated from a straylight eye model and applied to a real retinal image dataset composed of healthy subjects and patients with glaucoma and diabetic retinopathy. Results showed the capacity of the algorithm to detect and compensate the veiling glare degradation and improving the image sharpness up to 1000% in the case of healthy subjects and up to 700% in the pathological retinal images. This image quality improvement allows performing image segmentation processing with restored hidden spatial information after deconvolution.The optical quality of an image depends on both the optical properties of the imaging system and the physical properties of the medium in which the light travels from the object to the final imaging sensor. The analysis of the point spread function of the optical system is an objective way to quantify the image degradation. In retinal imaging, the presence of corneal or cristalline lens opacifications spread the light at wide angular distributions. If the mathematical operator that degrades the image is known, the image can be restored through deconvolution methods. In the particular case of retinal imaging, this operator may be unknown (or partially) due to the presence of cataracts, corneal edema, or vitreous opacification. In those cases, blind deconvolution theory provides useful results to restore important spatial information of the image. In this work, a new semi-blind deconvolution method has been developed by training an iterative process with the Glare Spread Function kernel based on the Richardson-Lucy deconvolution algorithm to compensate a veiling glare effect in retinal images due to intraocular straylight. The method was first tested with simulated retinal images generated from a straylight eye model and applied to a real retinal image dataset composed of healthy subjects and patients with glaucoma and diabetic retinopathy. Results showed the capacity of the algorithm to detect and compensate the veiling glare degradation and improving the image sharpness up to 1000% in the case of healthy subjects and up to 700% in the pathological retinal images. This image quality improvement allows performing image segmentation processing with restored hidden spatial information after deconvolution.
Author Ares, Jorge
Remón, Laura
Marcellán, María C.
Collados, María V.
Ávila, Francisco J.
AuthorAffiliation Departamento de Física Aplicada, Universidad de Zaragoza, 50009 Zaragoza, Spain; fatxutxa@unizar.es (J.A.); mcvidosa@unizar.es (M.C.M.); vcollado@unizar.es (M.V.C.); lauremar@unizar.es (L.R.)
AuthorAffiliation_xml – name: Departamento de Física Aplicada, Universidad de Zaragoza, 50009 Zaragoza, Spain; fatxutxa@unizar.es (J.A.); mcvidosa@unizar.es (M.C.M.); vcollado@unizar.es (M.V.C.); lauremar@unizar.es (L.R.)
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  givenname: Francisco J.
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  surname: Ávila
  fullname: Ávila, Francisco J.
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  orcidid: 0000-0002-1124-0363
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  fullname: Ares, Jorge
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  fullname: Marcellán, María C.
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  givenname: María V.
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  fullname: Collados, María V.
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  givenname: Laura
  surname: Remón
  fullname: Remón, Laura
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CitedBy_id crossref_primary_10_1016_j_cmpb_2022_107297
crossref_primary_10_3390_mi12121558
crossref_primary_10_1007_s11265_025_01958_7
crossref_primary_10_3390_jimaging10040089
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StartPage 73
SubjectTerms Age
Algorithms
artificial intelligence
blind deconvolution
Cataracts
Datasets
Deconvolution
Diabetes
Diabetic retinopathy
Edema
Glare
Glaucoma
Image degradation
Image quality
Image restoration
Image segmentation
intraocular straylight
Iterative methods
Optical properties
Performance evaluation
Physical properties
Point spread functions
Retina
Retinal images
retinal imaging
Richardson-Lucy deconvolution
Sharpness
Spatial data
Stray light
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Title Iterative-Trained Semi-Blind Deconvolution Algorithm to Compensate Straylight in Retinal Images
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