Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement

Vagus nerve stimulation (VNS) is a neuromodulation therapy for a broad and expanding set of neurologic conditions. However, the mechanism through which VNS influences central nervous system circuitry is not well described, limiting therapeutic optimization. VNS leads to widespread brain activation,...

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Bibliographic Details
Published in:	Neuron (Cambridge, Mass.) Vol. 110; no. 17; p. 2867
Main Authors:	Bowles, Spencer, Hickman, Jordan, Peng, Xiaoyu, Williamson, W Ryan, Huang, Rongchen, Washington, Kayden, Donegan, Dane, Welle, Cristin G
Format:	Journal Article
Language:	English
Published:	United States 07.09.2022
Subjects:	Animals Brain Cholinergic Agents - pharmacology Mice Nervous System Diseases - therapy Neuronal Plasticity - physiology Vagus Nerve Stimulation - methods neuromodulation motor cortex motor learning basal forebrain cholinergic plasticity learning vagus nerve stimulation reinforcement outcome
ISSN:	1097-4199, 1097-4199
Online Access:	Get more information
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