Pleomorphic adenoma with extensive squamous metaplasia: The first well-documented case involving the submandibular gland

Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was c...

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Bibliographic Details
Published in:Human Pathology Reports Vol. 27; p. 300600
Main Authors: Gaskin, David A., Reid, Alain, Gaskin, Pamela S.
Format: Journal Article
Language:English
Published: Elsevier Inc 01.03.2022
Elsevier
Subjects:
Pathology
Pleomorphic adenoma
Salivary gland
Salivary gland
Pleomorphic adenoma
ISSN:2772-736X, 2772-736X
Online Access:Get full text
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Summary:Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses.
ISSN:2772-736X
2772-736X
DOI:10.1016/j.hpr.2022.300600