Pleomorphic adenoma with extensive squamous metaplasia: The first well-documented case involving the submandibular gland
Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was c...
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| Published in: | Human Pathology Reports Vol. 27; p. 300600 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
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01.03.2022
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| ISSN: | 2772-736X, 2772-736X |
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| Abstract | Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands.
A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia.
Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses. |
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| AbstractList | Background: Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. Case report: A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. Discussion: Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses. Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses. AbstractBackgroundPleomorphic adenoma with extensive squamous metaplasia is relatively uncommon . Most reported cases in the English literature have involved the minor salivary glands. Case reportA 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. DiscussionPleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses. |
| ArticleNumber | 300600 |
| Author | Reid, Alain Gaskin, David A. Gaskin, Pamela S. |
| Author_xml | – sequence: 1 givenname: David A. surname: Gaskin fullname: Gaskin, David A. organization: Queen Elizabeth Hospital Barbados, Barbados – sequence: 2 givenname: Alain surname: Reid fullname: Reid, Alain organization: Faculty of Medical Sciences, University of the West Indies Cave Hill, Barbados – sequence: 3 givenname: Pamela S. surname: Gaskin fullname: Gaskin, Pamela S. email: pamela.gaskin@cavehill.uwi.edu organization: Faculty of Medical Sciences, University of the West Indies Cave Hill, Barbados |
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| Cites_doi | 10.4236/ojpathology.2013.33020 10.1186/1758-3284-4-24 10.1155/2015/856170 10.1097/PAS.0000000000000065 10.4103/0973-029X.151336 10.1007/BF02991485 10.1097/PAS.0000000000001252 10.4103/0970-9371.155226 10.1186/s13256-018-1941-3 10.1007/s12105-017-0854-6 10.1002/dc.20951 10.1097/01.MP.0000026053.67284.A3 10.1590/S1678-77572011000200016 10.4103/jomfp.JOMFP_200_17 10.4132/jptm.2018.07.15 10.1097/01.pas.0000213314.74423.d8 10.1007/s12105-013-0462-z 10.1097/PAS.0000000000000933 10.1002/cncy.21693 10.1093/jscr/rjv113 10.1016/S2096-6911(21)00079-0 |
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Plastic Reconstr. Surgery. doi: 10.1016/S2096-6911(21)00079-0 |
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| Title | Pleomorphic adenoma with extensive squamous metaplasia: The first well-documented case involving the submandibular gland |
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