Pleomorphic adenoma with extensive squamous metaplasia: The first well-documented case involving the submandibular gland

Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was c...

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Veröffentlicht in:Human Pathology Reports Jg. 27; S. 300600
Hauptverfasser: Gaskin, David A., Reid, Alain, Gaskin, Pamela S.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Elsevier Inc 01.03.2022
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Abstract Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses.
AbstractList Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses.
AbstractBackgroundPleomorphic adenoma with extensive squamous metaplasia is relatively uncommon . Most reported cases in the English literature have involved the minor salivary glands. Case reportA 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. DiscussionPleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses.
Background: Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. Case report: A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. Discussion: Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses.
ArticleNumber 300600
Author Reid, Alain
Gaskin, David A.
Gaskin, Pamela S.
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  email: pamela.gaskin@cavehill.uwi.edu
  organization: Faculty of Medical Sciences, University of the West Indies Cave Hill, Barbados
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Keywords Salivary gland
Pleomorphic adenoma
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Snippet Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary...
AbstractBackgroundPleomorphic adenoma with extensive squamous metaplasia is relatively uncommon . Most reported cases in the English literature have involved...
Background: Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the...
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SubjectTerms Pathology
Pleomorphic adenoma
Salivary gland
Title Pleomorphic adenoma with extensive squamous metaplasia: The first well-documented case involving the submandibular gland
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