Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro

Micro-electrode arrays (MEAs) are increasingly used to characterize neuronal network activity of human induced pluripotent stem cell (hiPSC)-derived neurons. Despite their gain in popularity, MEA recordings from hiPSC-derived neuronal networks are not always used to their full potential in respect t...

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Bibliographic Details
Published in:	Stem cell reports Vol. 16; no. 9; pp. 2182 - 2196
Main Authors:	Mossink, Britt, Verboven, Anouk H.A., van Hugte, Eline J.H., Klein Gunnewiek, Teun M., Parodi, Giulia, Linda, Katrin, Schoenmaker, Chantal, Kleefstra, Tjitske, Kozicz, Tamas, van Bokhoven, Hans, Schubert, Dirk, Nadif Kasri, Nael, Frega, Monica
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 14.09.2021 Elsevier
Subjects:	Action Potentials Animals Cell Culture Techniques Cell Differentiation Cells, Cultured Electrodes Genetic Association Studies - instrumentation Genetic Association Studies - methods human induced pluripotent stem cells Humans Lab-On-A-Chip Devices Mice micro-electrode arrays Microarray Analysis - instrumentation Microarray Analysis - methods Nerve Net neuronal differentiation neuronal network activity Neurons - cytology Neurons - metabolism human induced pluripotent stem cells neuronal network activity micro-electrode arrays neuronal differentiation
ISSN:	2213-6711, 2213-6711
Online Access:	Get full text
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