Structures and mechanisms of CRISPR RNA-guided effector nucleases

[Display omitted] •Incredible structural and mechanistic diversity in the CRISPR-Cas effector nucleases.•Divergent evolution of the type I (Cascade-Cas3) and type III (Csm/Cmr) effector nucleases.•Functional convergence between the type II (Cas9) and type V (Cpf1) effector nucleases. In the prokaryo...

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Bibliographic Details

Published in:	Current opinion in structural biology Vol. 43; pp. 68 - 78
Main Authors:	Nishimasu, Hiroshi, Nureki, Osamu
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.04.2017
Subjects:	Clustered Regularly Interspaced Short Palindromic Repeats Ribonucleases - metabolism RNA - genetics RNA - metabolism
ISSN:	0959-440X, 1879-033X, 1879-033X
Online Access:	Get full text
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