Recent advances in scaling-up of non-conventional extraction techniques: Learning from successes and failures

The impact of the extraction technologies on product yield and analytical profile is relevant. This review is aiming to discuss recent experiences of successes and failures in non-conventional extraction scaling-up, to better understand the challenges and designing of existing and new techniques. Un...

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Vydáno v:TrAC Trends in Analytical Chemistry Ročník 127; s. 115895
Hlavní autoři: Belwal, Tarun, Chemat, Farid, Venskutonis, Petras Rimantas, Cravotto, Giancarlo, Jaiswal, Durgesh Kumar, Bhatt, Indra Dutt, Devkota, Hari Prasad, Luo, Zisheng
Médium: Journal Article
Jazyk:angličtina
Vydáno: Elsevier B.V 01.06.2020
Elsevier BV
Elsevier
Témata:
[SDV.IDA]Life Sciences [q-bio]/Food engineering
[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering
analytical methods
Batch to flow
Bioactive compounds
Chemical and Process Engineering
energy
engineering
Engineering Sciences
environmental factors
Extraction scale-up
Extraction scale-up Ultrasonic-assisted extraction Supercritical fluid extraction Microwave-assisted extraction Batch to flow Bioactive compounds Green extraction
Food engineering
Green extraction
heat
Life Sciences
mass transfer
Microwave-assisted extraction
solvents
Supercritical fluid extraction
Ultrasonic-assisted extraction
Microwave-assisted extraction
Bioactive compounds
Green extraction
Ultrasonic-assisted extraction
Extraction scale-up
Batch to flow
Supercritical fluid extraction
ISSN:0165-9936, 1879-3142, 0165-9936
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Shrnutí:The impact of the extraction technologies on product yield and analytical profile is relevant. This review is aiming to discuss recent experiences of successes and failures in non-conventional extraction scaling-up, to better understand the challenges and designing of existing and new techniques. Understanding the crucial extraction factors at laboratory and pilot scale is of paramount value for the engineering work of scaling-up. Besides, a careful analysis and modelling of heat and mass transfer and energy consumption, the design of industrial extraction plants driven by economic and environmental factors, are well covered in the present review. Current trend strongly favors scaling-up of green approaches that consumes less organic solvent(s), involves minimal operational steps, provides high throughput capability and assures highest yield at lower costs. Current and future challenges in scaling-up extraction of bioactive compounds require a parallel development of suitable analytical methods to monitor the process and ensure high yield and quality. •Recent advances in extraction scale-up studies with non-conventional techniques.•Enabling technologies and analytical monitoring in industrial green extraction.•Hybrid techniques and continuous processes for extraction industrialisation.•Extraction kinetics and modeling for extraction optimisation.•Technology readiness levels (TRLs) in green extraction scaling-up.
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ISSN:0165-9936
1879-3142
0165-9936
DOI:10.1016/j.trac.2020.115895