Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data

The adaptive immune receptor repertoire (AIRR) contains information on an individuals' immune past, present and potential in the form of the evolving sequences that encode the B cell receptor (BCR) repertoire. AIRR sequencing (AIRR-seq) studies rely on databases of known BCR germline variable (...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 10; p. 129
Main Authors:	Gadala-Maria, Daniel, Gidoni, Moriah, Marquez, Susanna, Vander Heiden, Jason A., Kos, Justin T., Watson, Corey T., O'Connor, Kevin C., Yaari, Gur, Kleinstein, Steven H.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 13.02.2019
Subjects:	AIRR-seq Algorithms allele Alleles antibodies Bayes Theorem BCR Genotype Humans Immunoglobulins - genetics Immunology Myasthenia Gravis - immunology Sequence Analysis, DNA somatic hypermutation AIRR-seq BCR antibodies somatic hypermutation allele
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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